Up to three lanes of eastbound Highway 50 between 18th and 24th streets will be closed for construction from April 22-May 21.
The 11th Street ramp to eastbound Highway 80 also will be closed during the project. The 16th Street onramp and the connector ramps from eastbound Highway 50 to southbound Highway 99 and eastboard Business 80 will be closed May 7-21.
Up to three lanes of westbound Highway 50 between 18th and 24th streets will be closed for construction from May 27 through June 25.
The 16th Street offramp and the connector ramp from westbound Business 80 to westbound Highway 50 also will be closed June 11-25.
CalTrans said at least three lanes on the construction side of the highway will remain open to traffic during the project. No lanes in the opposite directions will be closed.